Omaha Office
13110 W Dodge Rd Suite B
Omaha, NE 68154
Phone: (402) 408-0017
Monday–Tuesday: 8 a.m.–7 p.m.
Wednesday–Thursday: 8 a.m.–5 p.m.
Friday: 8 a.m.–3 p.m.
Millard Office
12743 Q Street
Omaha, NE 68137
Phone: (402) 895-8001
Monday–Tuesday: 8 a.m.–7 p.m.
Wednesday–Thursday: 8 a.m.–5 p.m.
Friday: 8 a.m.–3 p.m.
Harness the natural regenerative power of growth factors in your blood with platelet-rich fibrin (PRF) injections at Preventive Medical Clinic in Omaha and Millard, Nebraska. The nourishing benefits of PRF bio filler injections minimize dark circles under the eyes, rejuvenate your cheeks, and enhance the buttocks.
What is platelet-rich fibrin?
Similar to platelet-rich plasma (PRP), platelet-rich fibrin is a bio filler collected from the blood. Platelets in the blood are rich in growth factors that increase the production of collagen and elastin. PRF contains a higher concentration of platelets, along with white blood cells and stem cells. The body creates fibrin to hold platelets around an injury. When PRF is injected into an area of the face, such as under the eyes, it modulates inflammation and spurs tissue repair, generating new cells, collagen, and elastin.
What is the difference between PRP and PRF?
The method of producing PRF and PRP is similar. In each case, a small sample of the patient’s blood is drawn and spun in a centrifuge. PRF requires less blood because it retains more of the blood’s elements. The centrifuge spins more slowly when producing PRF, which consists of fibrin, platelets, leucocytes, cytokines, and circulating stem cells. When the centrifuge spins faster, it separates platelets from the other substances to create PRP. PRF naturally forms (coagulates) into a gel that adds volume when injected and is absorbed more slowly than PRP.
Your Experience
The incredible service you expect from Kohll's is at the core of what we do here at Preventative Medical Clinic. When you visit us for a cosmetic or wellness appointment, you can anticipate the personal, knowledgeable care that's been our hallmark for more than 70 years.
Is PRF better than PRP?
PRF is considered the next generation of PRP. It releases growth factors for much longer than PRP, creating long-term benefits. Because PRF releases growth factors longer than PRP—up to a week compared to a few hours—it’s ideal for tissue regeneration and stimulating growth.
While both treatments use components of your own blood to stimulate natural rejuvenation, PRF offers several key advantages over PRP:
- Higher Concentration of Platelets:
PRF contains a greater number of platelets, white blood cells, and stem cells, which enhance tissue repair and collagen production. - No Additives or Anticoagulants:
Unlike PRP, PRF is 100% natural—no chemical additives are used. This allows for a slower, more sustained release of growth factors that continues for several days after treatment. - Extended Growth Factor Release:
PRF releases healing and growth factors over 7–10 days, compared to just a few hours with PRP, resulting in longer-lasting rejuvenation. - Natural Fibrin Matrix:
The fibrin matrix in PRF acts as a supportive scaffold, improving structure and helping growth factors stay active longer within the treated area. - Enhanced Regenerative Results:
The combination of stem cells, platelets, and fibrin in PRF promotes stronger, more comprehensive skin rejuvenation with visible improvements in tone, texture, and firmness.
Benefits of PRF injections
The primary benefit of PRF is that it employs your body’s own cells to promote the health of your skin. It also offers the following benefits:
- Treats circles under the eyes
- Minimizes wrinkles
- Reduces risk of side effects
- Stimulates skin healing
Because the product originates from the patient, it is very safe and is a natural alternative to synthetic fillers, which can cause allergic reactions or rejection.
PRF under the eyes for natural rejuvenation
PRF for under eyes treatments uses your body’s own platelets and growth factors to naturally refresh and strengthen the delicate skin in this area. This regenerative approach helps reduce dark circles, smooth fine lines, and restore lost volume without the use of synthetic fillers or additives.
By stimulating collagen and elastin production, PRF improves skin tone, texture, and firmness over time. The result is a brighter, more rested under eye appearance that looks completely natural and continues to improve gradually after treatment.
What happens during a PRF treatment?
The treatment begins with drawing a small amount of blood that’s placed in a centrifuge. As the blood spins, we’ll numb the treatment area to limit discomfort. The provider then uses a specialized syringe called a cannula to inject the PRF into the treatment area. In some cases, we’ll combine microneedling with the injections to enhance the results.
You can expect this entire procedure to last anywhere from 20 to 45 minutes, depending on your treatment area.
PRF Bio Filler FAQ
How many sessions of PRF do you need?
Most patients benefit from a series of 3 to 6 PRF treatments spaced about 4 to 6 weeks apart. This allows collagen stimulation and skin renewal to build gradually for smoother, longer-lasting results.
How long do results last?
Results typically last 1 to 2 years, depending on your skin condition and lifestyle factors. Many patients opt for maintenance sessions to maintain collagen production and skin quality.
Should I wait to exercise after PRF injections?
Yes. It’s best to avoid strenuous exercise for 24 to 48 hours after treatment to minimize swelling and allow the PRF to settle properly. You can usually resume light daily activity right away.
Get started
Discover all the ways PRF treatments at Preventative Medical Clinic can enhance your appearance naturally. To get started, request your appointment using our online form or call (402) 408-0017 to schedule an appointment.
